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pentobarbital will decrease the extent or outcome of fludrocortisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.pentobarbital will lower the level or influence of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Reasonable CYP3A4 inducers could minimize p